Gastrointestinal Mucosal Biopsy

Mucosal biopsy of the gastrointestinal tract.

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Prospective audit of mucosal biopsy specimens of the gastrointestinal tract.

AIMS To determine why mucosal biopsy specimens of the gastrointestinal tract were taken and whether they were justified on clinical or pathological grounds. METHODS A prospective audit of 190 consecutive biopsy specimens received in a university hospital histology department over six weeks. RESULTS The 31 separate presenting symptoms included diarrhoea (34%), abdominal pain (16%) and rectal...

Mucosal Biopsy Specimens

The effects of sodium butyrate and sodium bromo-octanoate (an inhibitor of P oxidation) on colonic mucus glycoprotein (mucin) synthesis have been assessed using tissue from colonic resection samples. Epithelial biopsy specimens were incubated for 16 hours in RPMI 1640 with glutamine, supplemented with 10% fetal calf serum and N-acetyl-[3H]glucosamine (3H]-Glc NAc), and differing concentrations ...

Monitoring Gastrointestinal Mucosal Perfusion

Serum and Antral Mucosal Biopsy Specimens

Helicobacter pyloni infection is associated with increased meal stimulated gastrin secretion, but the reason for this is unknown. Sequence specific radioimmunoassays were used to measure the concentration of ot-amidated gastrin, the total progastrin product, and somatostatin in biopsy specimens of human antral mucosa. The antral concentrations of ct-amidated gastrin and of total progastrin prod...